Indian Creek is a 31.0-mile-long (49.9 km)[1] tributary of the Youghiogheny River in Fayette County, Pennsylvania, in the United States.
Indian Creek drains the west slope of Laurel Hill in the Laurel Highlands and cuts a steep side canyon into the Youghiogheny Gorge to join the Youghiogheny River between Ohiopyle and Connellsville.